What Is Butalbital?

Butalbital is a barbiturate and a CNS stimulant primarily used to treat tension-type headaches, promote muscle relaxation, and manage pain.

It is often used in combination with other medications such as Acetaminophen, aspirin, caffeine, and sometimes codeine. This combination medication is prescribed when other non-opioid analgesics are ineffective or easily tolerated to help relieve pain and relax muscles.

Butalbital is also appropriate for targeting migraine and headache. Still, it is not recommended as a first-line treatment as it can impair alertness, increase the risk of chronic headache, and lead to dependence and addiction.

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Active And Inactive Ingredients

The active ingredient in Butalbital is Acetaminophen, aspirin, caffeine, and codeine. It contains certain inactive ingredients like colloidal silicon dioxide, pregelatinized starch, magnesium stearate, and gelatin capsules.

History And FDA Status

Butalbital was synthesized by Adolf Von Bayer in 1864 and was first introduced as a hypnotic in 1904. It was introduced in North America for medical practice in the 20th century.

The FDA approved Butalbital as a single-ingredient product on August 31, 1998. Whereas, the combination medication Butalbital/Acetaminophen/Caffeine was approved earlier on November 9, 1984, under the brand name Fioricet.

Why Butalbital Is Used?

Tension-type Headache

• Butalbital is commonly used to treat tension-type headaches when other non-barbiturate and non-opioid pain relievers fail to work or are tolerated.

Muscle Relaxation

• It also helps relax muscles in the brain due to its sedative effects and muscle-relaxing properties.

Pain Management

• This medication is also used as part of a combination therapy to relieve and manage pain.

Mechanism Of Action

This medication primarily acts by binding to the specific sites of inhibitory neurotransmitter gamma-aminobutyric acid (GABA). It enhances the effects of GABA and reduces the activity in the central nervous system (CNS) of the brain. Further, it produces sedative and muscle-relaxing impacts that help alleviate muscle tension, resulting in reduced stress and headaches.

It has a rapid onset of action, starting to work within 15 – 30 minutes of administration. Whereas, the sedative and muscle-relaxing effects are noticeable within 30 – 60 minutes. The effectiveness of Butalbital lasts for up to 35 hours, and reaches peak effects after 1 – 2 hours of ingestion.

Butalbital Formulations

Butalbital is available in combination with other medications as –

• Tablets
• Capsules
• Oral solution, and

Pill Identification

Strength – 50mg

Color – White

Shape – Round

Imprints – BAC 123

Dosage And Administration

Buy Butalbital online, and take your pills exactly as your doctor or healthcare provider recommends for safe and effective pain relief.

For Children

• This medication is not indicated for children under 12 years of age, and it must be given to children only on a doctor’s prescription.

For Adults

Capsules –

• Butalbital 50 mg/acetaminophen 300 mg/caffeine 40 mg: 1 or 2 capsules taken orally every 4 hours as needed, and do not exceed more than six capsules per day.

Tablets –

• Butalbital 50 mg/acetaminophen 325 mg/caffeine 40 mg: 1 or 2 tablets taken orally every 4 hours as needed, not to exceed more than six tablets per day.

Liquid Solution –

• Butalbital 50 mg/acetaminophen 325 mg/caffeine per 15 mL oral liquid: 15 to 30 mL taken orally every 4 hours as needed, not to exceed more than 90 mL per day.

For Older Adults

• People over 65 years are recommended to take a lower dose due to risk of overdose, which can severely affect their liver.

Who Cannot Use Butalbital?

Most children over 12 years and adults under 65 years can safely buy Butalbital online and use it. However, some people with certain health conditions are not recommended to use it.

You must tell your doctor or healthcare provider if you are –

• Allergic or hypersensitive to Butalbital
• Have porphyria
• Severe respiratory depression
• Lung disease, Asthma, or breathing difficulties
• Post-operative pain in Pediatric patients (children)
• Used MAOIs within the last 14 days
• Gastrointestinal obstruction (Paralytic ileus)
• Impaired consciousness or in a coma

Overdose Symptoms

If you buy Butalbital online, you must use it in adequate amounts to prevent the risk of overdose, which causes symptoms like –

• Hypotension
• Hypothermia
• Seizures
• Severe respiratory depression
• Cardiovascular collapse
• Liver failure
• In severe cases, coma or death

Adverse Effects Of Butalbital

Common Side Effects

• Lightheadedness
• Dizziness
• Dry mouth
• Drowsiness
• Sedation
• Nausea
• Vomiting
• Stomach pain
• Feeling weak or tired
• Loss of appetite
• Difficulty breathing

Serious Side Effects

• Skin reactions
• Severe allergic reactions
• Vision changes
• Blood disorder
• Respiratory depression
• Central nervous system (CNS) depression
• Addiction and withdrawal
• Liver damage

Warnings And Special Considerations

• Avoid using Butalbital if you have Asthma, COPD, or respiratory depression, as it increases the risk of worsened breathing.
• This medication is not indicated to be used during pregnancy, as it is associated with the risk of premature ductus.
• Do not use Butalbital if you are allergic to Acetaminophen, codeine, aspirin, or caffeine.

Preventions To Take While Using Butalbital

• Avoid alcohol and CNS depressant medication, as they can increase the risk of toxicity.
• Do not drive or use electronic equipment, as it may increase the risk of accidents due to drowsiness.
• Avoid increasing the dose, as it can lead to overdose, leading to liver damage and an increased risk of side effects.
• Contact a doctor before using Butalbital if you are pregnant or planning to become pregnant.
• Monitor for side effects, and seek immediate medical attention if you experience allergic reactions.

Is Butalbital Used In Pets?

Butalbital is not safe for pets, especially in combination with Acetaminophen and caffeine, unless specifically prescribed by a veterinarian. Acetaminophen is known to be extremely toxic in cats. It causes destruction of red blood cells and severe respiratory depression in both cats and dogs.

Avoid ingesting Acetaminophen, Butalbital, and caffeine to your dogs without a prescription or supervision of a veterinarian. Consult a doctor if your dog is experiencing pain for the best recommendations.

Other Brands

Butalbital is available in combination with other medications in various brands –

• Allzital
• Butapap
• Axocet
• Tancon
• Bucet
• Bupap
• Cephadin
• Dolgic
• Phrenilin
• Cedapap

Manufacturers

• Moehs Iberica
• Sieghfried AG
• Combrex cooperation
• Mallinckrodt Pharmaceuticals
• Chattem Chemicals Inc.
• Chemische Fabric Berg
• Pisgah Labs
• Strides Pharma Science Limited
• Teva Api India Private Limited

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Final Words

Due to containing Acetaminophen as an active ingredient, this medication carries a potential for abuse, misuse, and dependence when used regularly daily for a longer period.

 

This medication is not recommended for people with kidney and liver problems, as it can be life-threatening, leading to severe liver damage. Do not share this medication with others, use it in moderation, and avoid taking it too often.

 

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FAQ’s

 

• Does Butalbital cause sleepiness?

Yes, Butalbital can make you sleepy, causing drowsiness as a common side effect of this medication.

 

• Can Butalbital help with back pain?

There is no clinical evidence of the effectiveness of butalbital in treating or relieving back pain.

• How Butalbital Acetaminophen works?

Butalbital slows down the brain’s activity to alleviate muscle pain and stress. Whereas acetaminophen helps reduce the perception of pain.

 

• How long does Butalbital take to work?

It starts working within 15 – 30 minutes of ingestion and reaches its peak effects after 1 – 2 hours.

 

• What is Butalbital used for?

Butalbital is used to relieve tension-type headaches and muscle contraction.