About Buprenorphine 

Buprenorphine, sold under the brand Subutex, is a partial opioid agonist primarily used to treat Opioid Use Disorder (OUD) and pain. People with opioid addiction can buy Buprenorphine online to reduce opioid dependence and withdrawal symptoms.

This medication is classified as a partial agonist-antagonist, meaning it has agonist and antagonist activities at the opioid receptors. It is also used to treat acute and chronic pain caused by injury, surgery, underlying medical conditions, or nerve damage. 

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Active And Inactive Ingredients

Buprenorphine hydrochloride is the active ingredient in Buprenorphine. It also contains certain inactive ingredients like –

• lactose monohydrate
• cornstarch
• citric acid
• povidone
• sodium citrate
• mannitol
• magnesium stearate
• butylhydroxyanisole

History And FDA Status

In 1969, Researchers at Reckitt and Colman spent 10 years attempting to synthesize a more complex opioid structure than Morphine. 

It was first launched as an injection to treat severe pain in the United Kingdom in 1978. The sublingual formulation was released in 1982.

Buprenorphine was patented in 1965 and FDA-approved for medical use in the United States in 1981. This medication is included on the World Health Organization’s List of Essential Medicines. 

Uses Of Buprenorphine

Opioid Use Disorder (OUD)

• This medication is primarily prescribed to people with opioid use disorder and addiction to heroin. This medication helps reduce opioid dependence and withdrawal symptoms associated with opioid addiction. 
• It is a part of the comprehensive treatment program that includes counseling and behavioral training. 

Pain Management 

• Buprenorphine helps in managing acute pain caused by any injury or surgery, illness, trauma, or medical procedures. 
• Chronic pain is caused by underlying medical conditions and nerve damage. This medication is prescribed when other pain medications are ineffective.

Veterinary Use 

• It is a long-lasting pain reliever used after surgery in small animals. You can buy Buprenorphine online for mild to moderate pain management in dogs and cats.

Mechanism Of Action 

Buprenorphine works primarily by binding to opioid receptors in the brain and nervous system. It also activates the opioid receptors, but to a lesser extent than other opioids or morphine. 

It is an antagonist that binds to the mu-opioid receptors of the brain with higher affinity, resulting in less euphoria. This medication has a lower risk of severe side effects such as respiratory depression. 

Buprenorphine typically starts working within 30 – 60 minutes of use and reaches its peak effects after 1 – 2 hours. The effectiveness of this medication lasts for up to 12 – 24 hours after administration.

Buprenorphine Formulations

This medication comes in various formulations such as –

• Buccal film 
• Sublingual tablets 
• Transdermal patch 
• Injectable solution
• Extended-release injection 

Pill Identification 

Strength – 2mg

Color – White

Shape – Oval 

Imprints – B2

Dosage And Administration 

If you buy Buprenorphine online, you must take your pills exactly as your doctor prescribes for safe and effective use. 

For Adults 

• The typical dose is 16 mg tablets administered orally once daily. Do not exceed the dose of 24mg per day. 
• The maintenance dose after treatment, induction, or stabilization is 4 – 24mg taken sublingually daily. 

For Older Adults

• No specific adjustment required, as Buprenorphine is considered safer for older adults than any other opioid medication. 

Who Cannot Use Buprenorphine? 

Most adults can safely buy Buprenorphine online with a doctor’s prescription. However, this medication is not recommended for people with certain health conditions. 

Tell your doctor, and avoid using Buprenorphine if you have –

• Severe bronchial asthma
• Acute respiratory depression 
• Hypersensitivity to Buprenorphine or its ingredients
• Kidney impairment
• Sleep apnea
• Myasthenia gravis
• History of alcohol or drug addiction 
• Pregnant or breastfeeding women

Overdose Symptoms

Taking a higher dose of Buprenorphine can lead to overdose, causing symptoms like –

• Blurred vision 
• Severe confusion 
• Pinpoint pupils 
• Cold and clammy skin 
• Over sedation 
• Slowed heart rate
• Extreme weakness 
• Nausea 
• Vomiting 
• Stomach cramps
• Decreased blood pressure

Adverse Effects Of Buprenorphine

You may experience some common to serious side effects, whether you buy Buprenorphine online or from an offline store. 

Common Side Effects 

• Dizziness or drowsiness
• Headache
• Dry mouth 
• Nausea 
• Vomiting 
• Constipation 
• Muscle aches
• Swelling in the arms or legs

Serious Side Effects 

• Insomnia 
• Fatigue 
• Anxiety 
• Hallucinations
• Memory loss
• Liver problems 
• Respiratory depression 
• Serotonin syndrome 
• Allergic reactions

Warnings And Special Considerations

Read the warnings given below before you buy Buprenorphine online for Opioid use disorder or pain management. 

• Buprenorphine is not recommended as a first-line treatment in children and should be used under strict medical supervision. 
• This medication is not indicated to be used during pregnancy or breastfeeding. 

Preventions To Take While Using Buprenorphine 

You must take these preventative measures to prevent any serious side effects if you buy Buprenorphine online. 

• Avoid mixing or combining any CNS depressant medication while using Buprenorphine. 
• Avoid alcohol or any other substance, as it can lead to severe withdrawal symptoms.
• Be cautious and monitor for any side effects during the first 24 – 72 hours of taking the dose. 
• If you are using a Buprenorphine patch, avoid direct exposure to heat. 
• Tell your doctor if you are using any supplement, or have any history of kidney or liver problems, or mental illness. 

Is Buprenorphine Used In Pets?

Buprenorphine is commonly used in veterinary medicine for managing mild to moderate pain in dogs and cats. It is recommended to be used only on a veterinarian’s prescription for safe and effective pain relief. 

It is not officially FDA-approved for pets, but veterinarians prescribe it under certain medical conditions, such as after surgery or medical procedures. The most common side effect in pets is over-sedation, which can include agitation, changes in heartbeat, and gastrointestinal upset.

Other Brands 

Other brand names of Buprenorphine are –

• Buprenex 
• Simbadol 
• Zorbium
• Vetergesic 
• Buprenodale
• Buprecare

Manufacturers 

U.S manufacturers of Buprenorphine are –

• Perdue Pharma LP
• BioDelivery Sciences International 
• Invidor Inc.
• Braeburn Inc.

Where To Buy Buprenorphine Online On A Discount?

Looking to buy Buprenorphine online? Then, choose a trusted pharmacy like Xtra Pharmacy, which offers discreet delivery of quality medications. 

It is easy, convenient, and safe to buy Buprenorphine online from Xtra Pharmacy. Add 8mg Buprenorphine to your cart, and place your order to receive discreet overnight delivery to your doorstep. 

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Final Words 

Do not use Buprenorphine for a longer period. Otherwise, you may develop a dependency on it.

Avoid sharing this medication with older adults, and keep it out of reach of children to prevent any abuse and misuse. Buy Buprenorphine online on prescription for safe and effective use.

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FAQ’s

• Will Buprenorphine block Tramadol?

Buprenorphine is used with suboxone (which contains naloxone) that can block other opioid medications, including Tramadol. 

• Can Buprenorphine cause Constipation?

Yes, Buprenorphine can cause constipation, as it is one of the most common side effects of this medication. 

• Are Buprenorphine and Suboxone the same?

Buprenorphine and Suboxone are not the same, but they are closely related. Buprenorphine helps in treating opioid use disorder and pain. Whereas, Suboxone contains Buprenorphine and Naloxone as active ingredients. 

• How does Buprenorphine work?

Buprenorphine works by strongly attaching to the opioid receptors to relieve pain and reduce opioid cravings and withdrawal symptoms. 

• Can I take buprenorphine for pain?

Yes, you can take Buprenorphine if you are experiencing acute or chronic pain.